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Siddhartha Mukherjee argues that longevity research must address regenerative failure, including declining immune, bone, skin, and cartilage function, alongside diseases such as cancer and heart disease. He says this work needs basic-science funding and reliable biomarkers; current NIH priorities and the lack of long-term measures make progress difficult.
A Chan Zuckerberg BioHub initiative committed $1.8 billion to AI-ready biological data and virtual-cell research, with funding and datasets from CZI, the Department of Energy, NIH, Google DeepMind and Isomorphic Labs. Alex predicted plausible in-silico interventions for the top 5,000 diseases within two to three years, while saying regulatory approval remains a policy question.
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