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AI & TECH

OpenAI’s drug-development deal raises access questions

OpenAI’s Orchestra Bio acquisition adds agents that coordinate drug-development work across teams and outside partners.

OpenAI’s acquisition of Orchestra Bio adds a layer of coordination to its life-sciences tools, and puts a question of access in sharper focus. Orchestra’s agents organize development schedules, information and responses across company teams and outside research and manufacturing partners. OpenAI says scientists and program leaders will keep final decisions; the deal’s financial terms and integration date have not been disclosed.

Founded in fall 2022, Orchestra is joining GPT-Rosalind, OpenAI’s commercial biology product. OpenAI first released GPT-Rosalind as a research preview in April. The acquisition expands the company’s role from offering biology-focused AI tools to helping organize the work around drug development, without making OpenAI a drugmaker itself.

David Bennett argued that GPT-Rosalind’s restricted access for vetted U.S. enterprise customers, including Amgen and Moderna, could give large pharmaceutical companies an advantage over smaller drug developers. OpenAI also offers eligible university labs up to 30 free seats for 12 months. That plan widens access for some academic researchers, but does not resolve who can use the tools across the broader drug-development industry.

The question is also who shares in the value if the tools help produce a successful medicine. OpenAI CFO Sarah Friar has said licensing, intellectual-property agreements and outcome-based pricing could let the company capture some of that value. How those arrangements might work, and whether Orchestra’s agents will change access to GPT-Rosalind, remains unclear.

POLITICS

Vivek ramaswamy’s ohio ad divides republicans

Republicans in Ohio are split over Vivek Ramaswamy’s attack ad against Democratic gubernatorial candidate Amy Acton. JD Vance defended it, while Jon Husted said he would not have run it. On Breaking Points, Rich Barris called the tactic damaging and factually risky, warning it could hurt other Ohio Republicans.

Breaking Points reported on Oct. 22 that Ramaswamy’s campaign spent $4 million on the ad. It features Acton’s estranged mother, Donna Arthur, calling her daughter a liar. The campaign acknowledged running it, while saying it did not know what had happened between the two.

Acton’s brother, Phil Stearns, said she was sexually abused at age 12 by their stepfather, whom their mother remained married to. Stearns said Acton protected him from the abuse. Ramaswamy defended the ad by accusing Acton of lying and avoiding debates.

AI & TECH

AI circuitry may be easier to read than researchers thought

Nick Cammarata’s research challenges the idea that neural networks are inherently too tangled to interpret. He argues that researchers mistook blurry inspection tools and outdated model designs for evidence that AI circuitry was unreadable.

A famous example was a detector thought to respond to both cat faces and car fronts, a sign, researchers believed, that one neuron could hold unrelated concepts. Cammarata says it was actually responding to pointed, V-shaped features. He also claims that roughly nine out of ten detectors in modern OpenAI models have one primary function.

Cammarata reports that larger models can be easier to interpret, with broad detectors becoming more specific as models scale. OpenAI researcher Rohun called the work a historic scientific breakthrough and argued that inspecting a model’s internal plans could help reveal deception before it appears in the model’s answers.

In Brief

Viewers disagree over whether Fielder’s film shows Holmes changing or reveals another layer of performance.

Its awkward, staged approach makes the filmmaking itself part of the story.

China criticized the U.S. DeepSeek ban, which covers federal civilian systems, not individual users.

Commentators disagree over how much the order reflects security risks versus pressure on a Chinese competitor.

Musk’s proposed gift would give one SpaceX share to each of roughly 72 million American children.

Supporters see a lesson in ownership; the shares would be held for children until age 18.

Anthropic proposed putting 5% of its shares into a public-benefit fund, subject to shareholder approval.

Supporters and critics disagree over whether company leaders or ordinary people should control AI’s gains.

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