The Frontier

Your signal. Your price.

All-In with Chamath, Jason, Sacks & Friedberg 6d ago
  • Bryan Johnson argues high-dose psychedelics like psilocybin are a longevity therapy, not just mental health medicine, because they reset metabolic and neural aging pathways.

  • In a quantified experiment, Johnson found a high 25-milligram dose of psilocybin lowered his blood glucose from the 99.5th to the 99.9th percentile, a shift he says is more dramatic than what metformin achieves.

  • The key longevity benefit Johnson observes is a durable, childlike neuroplastic state post-experience, evidenced by a quieted internal monologue and simple, non-defensive conflict resolution.

  • Johnson's quantified approach aims to reframe the psychedelic experience from spiritual anecdote to a measurable biomarker reset of the aging clock.

Beyond your filters

  • The ECB and Bank of England's single inflation mandates force them to hike rates when oil spikes, unlike the Fed's dual mandate.

    Beyond your filtersFedRegulationvia Forward Guidance
  • Enjeti argued that Trump's actions deprive the public of the ability to laugh at his antics, because the resulting death and destruction are too grave.

    Beyond your filtersMediaCorruptionvia Breaking Points with Krystal and Saagar
  • The hosts state that Monero hides virtually all transaction details, making it the world's most private privacy token, according to Investigator from Ungovernable Misfits.

    Beyond your filtersPrivacyvia Ungovernable Misfits

Today's edition is light (4 results)